trai-guṇya-viṣhayā vedā nistrai-guṇyo bhavārjuna
nirdvandvo nitya-sattva-stho niryoga-kṣhema ātmavān || 45||

My Understanding : Temporary comforts are not true happiness. Running away from problems is not the solution. You must face challenges when they arise, as you cannot escape the effects of your karma. Whatever comes your way—whether good or bad—you must confront it. The materialistic world is tainted by the influence of the three gunas (modes of nature), which pollute the mind and distract from true fulfillment.